Executive LeadershipKoon Yan "Chris" Pak, Ph.D.Chief Executive Officer and Chairman of the BoardDr. Chris Pak brings three decades of experience in the biopharmaceutical industry. Chris was formerly with Centocor, now a subsidiary of Johnson and Johnson, where he invented and developed novel radiopharmaceuticals and participated in the filing of twenty IND applications for cancer and cardiovascular diseases. He has founded and led multiple societies promoting Nuclear Medicine and Molecular Imaging and entrepreneurship organizations. Steven Brem, MD.Chief Medical OfficerDr. Brem is the Chief of Neurosurgical Oncology, Co-director of Penn Brain Tumor Center and Professor of Neurosurgery at University of Pennsylvania, Perelman School of Medicine. Dr. Brem is a renowned clinical research scientist who sits on the scientific/medical advisory boards of several cancer research associations including American Association of Cancer Research, American Brain Tumor Association and Brain Tumor Action Network among others. Dr. Brem has extensive clinical research experience in many types of tumors. He has reviewed and approved 127 tumor trial protocols in University of Pennsylvania and at Moffitt Cancer Center. Dr. Brem is currently the principle investigator of six cancer trials, including two NIH funded and four industry sponsored trials. He has published more than 100 clinical research articles in peer-reviewed journals and presented more than 100 posters in medical conferences such as ASCO (American Society of Clinical Oncology). Jeffrey A. Mattis, Ph.D.Senior Vice President of Scientific & Regulatory Affairs, Board DirectorDr. Mattis is a biopharmaceutical executive with more than 30 years’ experience in the technical development of biopharmaceuticals. Dr. Mattis previously served as Vice President of Pharmaceutical Development for Centocor. Dr. Mattis was instrumental in the technical development of several biopharmaceuticals approved for the US and multinational markets. These include ReoPro®, an anti-platelet drug for use in coronary angioplasty; Remicade®, a drug for treatment of Crohn’s disease and rheumatoid arthritis; and Myoscint®, a cardiac imaging agent. Brian D. Gray, Ph.D.Senior Vice President of ResearchDr Gray has more than 25 years’ experience in the design and synthesis of novel compounds for biomedical research, diagnostics and drug delivery, with special expertise in fluorescent dyes and lipophilic agents. Following a research career at SmithKline Beckman, Dr. Gray co-founded Zynaxis, Inc., a biotech, as Director of Medicinal Chemistry. Later as V.P. of Chemical Research for PTI Research, Inc., he provided contract and custom chemistry services for life sciences and designed novel research reagents for neuronal tract tracing (NeuroVue® dyes) and cell tracking (CellVue® dyes). Dr. Gray earned a Ph.D. from the University of Dundee, Scotland, and carried out post-doctoral research in complex organic molecule synthesis at Oregon State University. He has been Principal Investigator in multiple grants. Michael Silvon, Ph.D., MBASenior Vice President of Business DevelopmentDr. Silvon has driven profitable, pragmatic life sciences operations over the breadth of small and large molecule drug development; creating, fixing and growing multiple high science, heavily regulated businesses as a senior executive for Charles River Labs, Bioanalytical Systems and ICI/Zeneca. He orchestrated six acquisitions and integrated and ran businesses for three of these long-term. As VP Global Biopharmaceutical Services for Charles River Labs, he restructured and consolidated five global sites into a global leader in molecular biology, virology and microbiology services. Mike advises Chronic Airways Therapeutics and also serves as a Director for Claro Labs and Spark Insights. Jianwei Xu, Ph.DChief Business OfficerDr. Xu has a decade of consulting and investment experience in the pharmaceutical industry. His most recent positions include Director of Decision Analysis and Portfolio Management at Johnson & Johnson Pharmaceutical R&D and Decision Analysis Advisor at Chevron. Previously, as an associate at McKinsey & Company he supported major pharmaceutical companies, planning and implementing strategies to optimize competitive position. He has identified and evaluated major trends impacting Pharmaceutical industry valuation and guides clients to exploit them to unlock value. John Farah, Ph.DExecutive AdvisorDr. Farah has broad expertise in life sciences business development, strategic analysis, R&D, ex-US commercialization, and scientific/clinical affairs, with a focus on products for hematology & oncology, neurosciences & pain, and infectious/inflammatory disorders. Board Of DirectorsKoon Yan "Chris" Pak, Ph.D.Chief Executive Officer and Chairman of the BoardDr. Chris Pak brings three decades of experience in the biopharmaceutical industry. Chris was formerly with Centocor, now a subsidiary of Johnson and Johnson, where he invented and developed novel radiopharmaceuticals and participated in the filing of twenty IND applications for cancer and cardiovascular diseases. He has founded and led multiple societies promoting Nuclear Medicine and Molecular Imaging and entrepreneurship organizations. Ji Li, Ph.D.Board DirectorAn accomplished business creator, Dr. Li has orchestrated investment in and headed multiple life science businesses. In addition to his role as COO at MTTI, Dr. Li is President & CEO and co-founder of UFOVAX, Inc. commercializing Scripps Institute’s one component, self-assembling protein nanoparticle (1c-SApNP) vaccine platform technology generating promising candidates for HIV, HCV, Ebola, RSV, MERS and, most recently, COVID-19. Jeffrey A. Mattis, Ph.D.Senior Vice President of Scientific & Regulatory Affairs, Board DirectorDr. Mattis is a biopharmaceutical executive with more than 30 years’ experience in the technical development of biopharmaceuticals. Dr. Mattis previously served as Vice President of Pharmaceutical Development for Centocor. Dr. Mattis was instrumental in the technical development of several biopharmaceuticals approved for the US and multinational markets. These include ReoPro®, an anti-platelet drug for use in coronary angioplasty; Remicade®, a drug for treatment of Crohn’s disease and rheumatoid arthritis; and Myoscint®, a cardiac imaging agent. Dr. Peter E. Grebow, Ph.D.Board DirectorFounder and President of P.E. Grebow Consulting, Inc. since 2011. Dr. Grebow has more than twenty-five years of experience in the pharmaceutical industry, last serving as an EVP of Research & Development of Eagle Pharmaceuticals Inc. Sean WangFounder & CEO, B&W TEK, Board DirectorAn accomplished entrepreneur, inventor, scientist and engineer Dr. Wang has launched, incubated, and financed more than a dozen companies, most of them based on the generation, manipulation, and detection of light. Scientific AdvisorsProfessor Richard Wahl, M.D., FACRProfessor of Radiology and Radiation Oncology Washington University in St Louis School of MedicineProfessor Wahl is a Professor of radiology and radiation oncology at Washington University School of Medicine in St. Louis. From 2014-2023 he served as the Elizabeth E. Mallinckrodt Professor and Chair of the Department of Radiology and Director of the Mallinckrodt Institute of Radiology at Washington University School of Medicine in St Louis. He served from 2000-2014 as the inaugural Henry N. Wagner, Jr. Professor of Nuclear Medicine and director of nuclear medicine at Johns Hopkins University School of Medicine in St. Louis. Prior to that he served as a professor at the University of Michigan in Ann Arbor, MI. Professor Wahl is recognized as a world leader in the field of targeted radiopharmaceuticals for diagnosing and treating cancer. With an emphasis on PET and multi-modality imaging, such as PET-CT, his work enables precision diagnosis of a broad array of human cancers and other serious diseases. Professor Wahl is one of the inventors of radio-immunotherapy of lymphoma, which is a combination of radiotherapy and immunotherapy that facilitates targeted treatments. He has also been an inventor of a number of FDA approved medical devices, such as radionuclide guided biopsy. Professor Wahl holds 18 radiology patents and has published more than 500 peer-reviewed scientific papers and several books. He has served as a chairman of the American Board of Nuclear Medicine (ABNM), president of the Institute for Clinical PET (ICP) program, refresher course chair for Radiological Society of North America and on multiple NIH study sections. He was elected as a member of the US National Academy of Medicine in 2015. More recently, Professor Wahl served as 2021-22 president of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) and founded the Mars Shot for Nuclear Medicine initiative. He has received multiple professional awards including the Hounsfield, Saul Hertz, Tetalman, Berson-Yalow and deHevesy awards and the 2023 Washington University Alumni Association achievement award. He remains actively engaged in clinical and research applications of radiotheranostics. Daniel Pryma, MDGerd Muehllehner Professor of Radiology, Chief of the Division of Nuclear Medicine Imaging and Therapy at the Perelman School of Medicine at the University of PennsylvaniaDaniel Pryma, MD is the Gerd Muehllehner Professor of Radiology, Chief of the Division of Nuclear Medicine Imaging and Therapy at the Perelman School of Medicine at the University of Pennsylvania and the Associate Director for Clinical Research at the Abramson Cancer Center of the University of Pennsylvania. He also serves as Chair of the Imaging Committee for NRG Oncology. Dr. Pryma’s primary research interests are in therapeutic radiopharmaceuticals, particularly alpha particle emitters, and companion diagnostics for both solid and liquid cancers. He directs a pre-clinical radiopharmaceutical laboratory in addition to his extensive work in clinical trials spanning from first in human through registrational and post-registrational trials. He is engaged in multiple clinical programs: Neuroendocrine Tumor Program, Endocrine Tumor Program and Genitourinary Tumor Program. He graduated with honors from Loyola University of Chicago, Stritch School Of Medicine in 2002 and completed his medical training at Memorial Sloan-Kettering Cancer Center having been board certified in Nuclear Medicine in 2005. Dr. Pryma has 129 publications in clinical practice, PET, PET/CT, Radiopharmaceutical Therapy, Radioimmunotherapy and Nuclear Oncology. H. William Strauss, M.D.Clinical Director, Nuclear Medicine Service at Memorial Sloan-Kettering Cancer CenterDr. Strauss is the Clinical Director, Nuclear Medicine Service at Memorial Sloan-Kettering Cancer Center. Formerly he was Professor of Radiology and Chief of Nuclear Medicine at Stanford University School of Medicine and Vice President of Bristol-Myers-Squibb. Earlier Dr. Strauss was Professor at the Harvard Medical School and Massachusetts General Hospital for almost two decades. Sean Yan Xue Xian MD, DABNMSenior Consultant Physician at Singapore General HospitalDr. Yan is an experienced senior consultant physician with Singapore General Hospital and a visiting consultant with National Cancer Center Singapore since 2015. Ban An Khaw, Ph.D.Director of the Center for Drug Targeting and Analysis at Northeastern UniversityDr. Khaw is a leading authority in cardiac imaging and new technology development. He has been with the Harvard Medical School and the Massachusetts General Hospital, Division of Nuclear Medicine, Department of Radiology and the Cardiac Unit for three decades and is currently Director of the Center for Drug Targeting and Analysis, at the Bouvè College of Pharmacy and Health Sciences at Northeastern University. Dr. Khaw is a pioneer in the application of immunological methods in the diagnosis of cardiovascular diseases. He co-developed Myoscint for myocardial infarct detection. He has chaired multiple symposia, authored nearly 300 publications and holds 15 patents. Currently, he is on the editorial boards of Bioconjugate Chemistry and American Journal of Nuclear Cardiology. Professor Fabian Kiessling, M.D., Ph.D.Institute of Experimental Molecular Imaging at the Helmholtz Center of Applied Engineering of the RWTH-UniversityProfessor Fabian Kiessling has headed the Institute of Experimental Molecular Imaging at the Helmholtz Center of Applied Engineering of the RWTH-University in Aachen, Germany since 2008. News
Posted 9/12/2024 - MTTI reports on fast-acting sprayable molecule to visualize tumors for real-time fluorescence-guided cytoreductive surgery
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Posted 9/10/2024 - MTTI at the 2nd Annual Targeted Radionuclide Pharmaceuticals Supply Chain & Manufacturing Summit
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Posted 5/21/2024 - MTTI reports on 225Ac-EBTATE and 177Lu-EBTATE radiopharmaceuticals at 2024 Society of Nuclear Medicine and Molecular Imaging annual meeting
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Posted 9/29/2023 - Molecular Targeting Technologies, Inc. TO PRESENT EVATHERA, LONG-ACTING PEPTIDE RECEPTOR RADIONUCLIDE THERAPY PLATFORM, AT BIOFUTURE™ 2023
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Posted 9/12/2023 - MTTI ANNOUNCES THE APPOINTMENT OF DR. JERRY HUANG TO THE CLINICAL TEAM
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Posted 8/01/2023 - Molecular Targeting Technologies, Inc. and Molecular Theranostics Center of Singapore receive HSA approval for Clinical Trial Authorization for EBTATE® in Nasopharyngeal Cancer
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Posted 6/21/2023 - MTTI Highlights Promising One-Year Follow-Up On Ebtate Treatment Of Neuroendocrine Cancer Patients Without Amino Acid Infusion
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Posted 6/19/2023 - MTTI Annouces Favorable Three-Year Follow-Up For Ebtate In
Neuroendocrine Tumors
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Posted 12/8 /2022 - MTTI obtains FDA allowance of Investigational New Drug (IND) for Hürthle Cell Thyroid Cancer
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Posted 12/5 /2022 - MTTI Receives Chinese Patent for EVATHERA Technology
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Posted 6/29 /2022 - MTTI doses first patient in EBTATE neuroendocrine tumor clinical trial
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Posted 6/9 /2022 - Molecular Targeting Technologies, Inc. features EBTATE advances at the 2022 SNMMI meeting in Vancouver, BC.
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Posted 4/13 /2022 - ITM and MTTI Sign Clinical Supply Agreement for n.c.a. Lutetium-177
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Posted 1/25 /2022 - Molecular Targeting Technologies, Inc., Thomas Jefferson University and North China Pharmaceutical Co., Ltd announced the Chinese approval for a Rabies drug
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Posted 12/03 /2021 - MTTI partners with Evergreen to manufacture EvaThera platform of radiopharmaceuticals
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Posted 12/02/2021 - MTTI and Monrol have signed a clinical supply agreement for Lu-177 n.c.a.
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Posted 10/19/2021 - Molecular Targeting Technologies, Inc. Announces Spray Technology That Lights Up Tumors
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Posted 09/21/2021 - Molecular Targeting Technologies, Inc. and Temple University Announced Patent approval for Anti-thrombotic Agents
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Posted 05/11/2021 - Molecular Targeting Technologies, Inc. and University of Antwerp begin First-in-Human study of TDURA diagnostic for early detection of response to colon cancer therapy
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Posted 04/13/2021 - Molecular Targeting Technologies, Inc. Announces a new PET imaging agent for Rapid Monitoring Tumor Response to Therapy.
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Posted 03/23/2021 - Xiaoyuan (Shawn) Chen, PHD, Discusses New Treatment for Late-Stage Neuroendocrine Tumors.
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Posted 03/23/2021 - Molecular Targeting Technologies, Inc. Says New Radiotherapeutic is Effective
and Less Toxic for Neuroendocrine Tumor Patients.
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Posted 03/19/2021 - New Treatment Proves More Effective and Less Toxic for Neuroendocrine Tumor Patients.
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Posted 03/09/2021 - Isotopia Molecular Imaging and Molecular Targeting Technologies have
signed a clinical supply agreement for Lu177 n.c.a.
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Posted 03/02/2021 - FDA approves Investigational New Drug (IND) for Neuroendocrine Tumors from
Molecular Targeting Technologies, Inc.
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Posted 07/31/2020 - New PET Radiotracer Proven Safe and Effective in Imaging Malignant Brain Tumors
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Posted 07/10/2020 - Molecular Targeting Technologies, Inc. Announces Presentations at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2020 Annual Meeting
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Posted 07/10/2020 - First-in-Human Study of a Long-acting αvβ3Integrin Targeting Molecule 64Cu-NOTA-EB-RGD in Healthy Volunteers and GBM Patients
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Posted 07/10/2020 - Early Studies Show Multiple Cycles of EBTATE are Well Tolerated and Effective in Treating Neuroendocrine Tumors
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Posted 10/28/2019 - MTTI Receives Global Rights from NIH for Integrin-targeting Radiotherapeutics to treat GBM and Lung Cancer
Posted 06/22 /2019 - Early Studies Show EBTATE is Well Tolerated and Effective in Treating
Neuroendocrine Tumors
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Posted 06/18/2019 - Molecular Targeting Technologies, Inc. Announces Closing of Series A Financing
to Develop Novel Neuroendocrine Neoplasm Drug
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Posted 06/17/2019 - Molecular Targeting Technologies, Inc. Announces Presentations at the Society of Nuclear
Medicine and Molecular Imaging (SNMMI) 2019 Annual Meeting
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Posted 05/13/2019 - EY Announces Chris Pak of Molecular Targeting Technologies, Inc. as
Entrepreneur Of The Year® 2019 Award Finalist in Greater Philadelphia
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Posted 10/08/2018 - Molecular Targeting Technologies, Inc. Wins Exclusive License for Novel Neuroendocrine Neoplasm Drug from NIH.
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Posted 9/29/2017 - Molecular Targeting Technologies, Inc. Wins Award from
“RESI Boston 2017” Innovation Challenge
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Posted 6/27/2017 - TumorVue Image Wins the 2017 MILabs Image of the Year Award
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Posted 12/05/2016 - MTTI announces that response of colorectal cancer to treatment can be detected as early as one day after treatment
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Posted 08/18/2016 - New milestone: 癌症治療新曙光 國衛院與泰緯生技攜手抗癌
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Posted 01/08/2016 - MTTI Receives Multimodality DPA Technology Patent
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Posted 05/15/2015 - MTTI receives expanded patent approval for 99mTc-Duramycin technology to target programmed cell death
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Posted 05/08/2015 - World news on Novel Cancer Therapeutic
Posted 05/06/2015 - MTTI announces the capability of PSVue 794 to non-invasively image arthritis
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Posted 05/06/2015 - MTTI announces the capability of PSVue 794 to non-invasively image arthritis
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Posted 05/06/2015 - MTTI announces the capability of PSVue 794 to non-invasively image arthritis
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Posted 04/22/2015 - MTTI Smith Molecular Probe on WSBT View Video
Posted 04/22/2015 - Dr. Bradley Smith speaks about the potential clinical applications of Cell-Death Imaging Agent View Video
Posted 04/18/2015 - 國家衛生研究院暨美國Molecular Targeting Technologies公司於2015美國癌症研究協會(AACR)共同發表新穎癌症治療法合作案之研發成果
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Posted 04/17/2015 - MTTI and National Health Research Institutes Present a Novel Cancer Therapeutic at 2015 AACR
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Posted 10/24/2014 - MTTI receives patent approval for technology to identify dead and dying cells in patients
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Posted 08/04/2014 - MTTI and National Health Research Institutes Have Joined Forces in Developing Novel Cancer Therapeutics
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Posted 08/04/2014 - 國 家衛生研究院暨美國 家衛生研究院暨美國 家衛生研究院暨美國 家衛生研究院暨美Molecular Targeting Molecular Targeting Molecular Targeting 公司
合作進行新穎癌症治療法之研發 合作進行新穎癌症治療法之研發 合作進行新穎癌症治療法之研發 合作進行新穎癌症治療法之研發 合
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Posted 06/13/2014 - Chris Pak received 2014 Lifetime Achievement Award from CASNMMI
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Posted 02/26/14 - Philadelphia Business Journal Recognizes MTTI for 2013 Innovation Award
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Posted 06/21/13 - Real time assessment of tumor response presentation wins the Innovation Competition
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Posted 11/28/12 - Notre Dame and MTTI Awarded Patent for Fluorescent Dye Technology
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Posted 8/2/12 - MTTI licenses Novel Targeting Agent from Medical College of Wisconsin
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Posted 5/10/11 - MTTI licenses robust NIR dye technology from Massachusetts General Hospital
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Posted 10/12/10 - Jefferson Awarded Multi-Million Dollar NIH Grant
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Posted 9/22/10- Zn_DPA Cardiac Imaging Study Wins Competition
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Posted 3/19/10 - University of Notre Dame and MTTI in Deal
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Posted 3/1/10 - Molecular Targeting Technologies, Inc. Licenses Cell Targeting Technology from the University of Notre Dame
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Posted 3/2/09 - LI-COR Sciences and MTTI Introduce CellVue® Dye Kits for Fluorescent Labeling of Cell Membranes
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Posted 8/23/08 - MTTI has B-Bridge Inc. as a distributor for Japan.
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Posted 8/22/08 - MTTI has engaged Dundee Cell Products as a distributor for Europe.
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Posted 4/22/08 - MTTI will collaborate with Bexion to develop a novel nanovesicle for molecular imaging of tumors.
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Posted 1/8/08 - MTTI and GENSEEN Partner to Develop Breast Cancer Gene Imaging Agent
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